Thursday 25 February 2016
BIOCHEMISTRY II YEAR
BIOCHEMISTRY III YEAR
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| II B.Sc., SEMESTER IV MAJOR CORE ELECTIVE: 1 (OPTIONAL): GENETICS |
| Unit I |
| Mendelian traits in man |
| pedigree charts |
| Multiple alleles: |
| Blood group inheritance – ABO, MN, Rh |
| Blood group inheritance – ABO, MN, Rh |
| applications |
| Quantitative inheritance |
| polygenic inheritance – skin colour in man |
| polygenic inheritance – skin colour in man |
| Linkage: Morgan’s experiment. |
| Crossing over: Kinds, theories and cytological basis. |
| Unit II |
| Sex determination: Theories |
| Heterogametic |
| genic balance |
| haploidy |
| sex reversal |
| hormones and environmental factors |
| Non disjunction – types |
| gynandromorphism – origin. |
| Sex determination in man |
| sex determining genes |
| Lyon’s hypothesis. |
| Sex linked inheritance |
| X linked genes in man |
| color blindness and hemophiliac |
| Y linked gene |
| trichosis |
| Sex limited and sex influenced genes |
| Unit III |
| Introduction to gene function |
| Role of genes in metabolism |
| metabolic disorders associated with phenylalanine metabolism |
| phenylketonuria; |
| disorders associated with Hb |
| Genetic counseling |
| : Determining risks – consanguinity |
| Prenatal diagnosis: |
| ultrasound scanning |
| amniocentesis chorionic villi sampling |
| AFP test |
| management of genetic disorders. |
| Unit IV |
| Mutation: major molecular mechanism |
| mutagens viz., radiation and chemicals. |
| Variation in chromosomes: |
| aneuplodiy – types |
| syndromes in man |
| Down’s, Turner’s and Klinefelter`s Polyploidy |
| Mutation detection-ClB method |
| Population genetics: |
| Hardy-Weinberg equilibrium |
| frequency of recessive and multiple alleles. |
| Changes in gene frequencies |
| Unit V |
| Human chromosome complement |
| Karyotype preparation |
| somatic cell hybridization |
| gene mapping |
| Human behavior and genes |
| Psychosis and schizophrenia. |
| Cancer genetics: Oncogenes |
| proto oncogenes antioncogenes |
| – oncoproteins and gene regulation. |
II B.Sc., SEMESTER IV ALLIED 5 (OPTIONAL): MICROBIOLOGY-APPLIED |
| Unit I |
| INDUSTRIAL MICROBIOLOGY: |
| Fermentation Products |
| enzymes, antibiotics, alcohol |
| enzymes, antibiotics, alcohol |
| microbes involved, fermentation process of ethyl alcohol |
| microbes involved, fermentation process of vinegar |
| microbes involved, fermentation process of penicillin |
| Effluent treatment. |
| Unit II |
| FOOD MICROBIOLOGY |
| Normal flora of fresh food |
| food spoilage |
| food poisoning |
| Physicochemical methods in food preservation |
| DAIRY MICROBIOLOGY: |
| Normal flora of milk |
| pasteurization |
| milk products |
| Milk borne diseases. |
| Unit III |
| AGRICULTURAL AND AQUATIC MICROBIOLOGY |
| AGRICULTURAL AND AQUATIC MICROBIOLOGY |
| Soil microorganisms |
| Types, influence on soil |
| nitrogen cycle |
| nitrogen fixation |
| soil fertility |
| biofertilizer |
| Biogas |
| An introduction to marine microbes. |
| Unit IV |
| An introduction to Medical Microbiology. |
| Types and analysis of air microorganism |
| air borne diseases |
| chicken pox, and measles. |
| meningitis |
| Types and analysis of water microorganism |
| water borne diseases – cholera |
| water borne diseases –polio |
| Zoonotic diseases |
| Anthrax prevention cure |
| Rabies prevention cure |
| Swine flu prevention cure |
| UnitV |
| MEDICAL MICROBIOLOGY |
| Common bacterial, viral diseases of man |
| Common bacterial, viral diseases of man |
| diphtheria |
| tuberculosis |
| pneumonia |
| whooping cough |
| typhoid |
| cholera |
| leprosy |
| tetanus |
| polio |
| viral hepatitis |
| AIDS – causative organism |
| clinical symptoms, preventive measures. |
| II B.Sc., SEMESTER –III MAJOR CORE 5 - HUMAN PHYSIOLOGY |
| Unit I |
| DIGESTIVE AND CIRCULATORY SYSTEM: |
| Gross anatomy of the Gastro- Intestinal tract |
| Intestinal tract– types of glands and their secretion |
| Basic structure and function of heart |
| rhythmicity of heart |
| origin and conduction of heart beat |
| cardiac cycle |
| heart sounds |
| Blood pressure |
| heart rate |
| Cardiac output |
| electrocardiogram. |
| Unit II |
| RESPIRATORY SYSTEM: |
| Respiration - Definition |
| Basic structure of lungs |
| transport of gases (CO2 & O2) |
| Body fluids – |
| Extracellular fluid |
| plasma volume |
| interstitial fluid |
| transcellular fluid |
| intracellular fluid |
| ionic composition of body fluids |
| imbalances in sodium and potassium lends |
| body buffers |
| lymph-formation |
| composition and flow |
| Unit III |
| EXCRETORY SYSTEM: |
| Excretion: Basic structure and function of kidney |
| glomerular filtration rate |
| Tubular Transport maximum |
| tubular load, plasma clearance |
| tubular load, plasma clearance |
| Formation of urine – Threshold substances |
| filtration pressure |
| filtration |
| reabsorption |
| secretion |
| acidification |
| Normal and abnormal constituents of urine. |
| Physiology of reproduction. |
| Unit IV |
| NERVOUS AND MUSCULAR SYSTEM: |
| Structure of neuron |
| nerve impulse |
| neurotransmission |
| synapse |
| chemical synapse |
| electrical synapse |
| functional properties of nerve fibre |
| Action potential |
| Reflex action and reflex arc |
| Molecular organization |
| contraction of striated muscles |
| mechanism of excitation |
| neuromuscular functions |
| Biochemistry of muscle contraction. |
| Unit V |
| BASIC ENDOCRINOLOGY |
| Introduction to Hormones |
| Mode of action of hormones. |
| Hypothalamus and Hypophysis |
| Thyroid, Parathyroid and Pancreas |
| Adrenal hormones |
| Gonadal hormones |
II B.SC., SEMESTER III MAJOR CORE 4: ANALYTICAL BIOCHEMISTRY |
| Unit I |
| SPECTROMETRIC METHODS |
| Principles of electromagnetic radiation |
| Principles of energy |
| Principles of wavelength |
| Principles of absorption |
| Principles of emission spectra |
| Spectro fluorometry |
| Spectro fluorometry instrumentation |
| Spectro fluorometry applications in vitamin assays |
| flame photometry |
| atomic absorption spectrophotometry |
| atomic absorption spectrophotometry applications |
| NMR spectroscopy, IR spectroscopy |
| FT-IR spectroscopy. |
| Unit II |
| CHROMATOGRAPHY |
| Paperchromotography |
| Thin layer chromatography |
| Column chromatography |
| Molecular sieve chromatography |
| Gas – Liquid chromatography |
| Adsorption |
| Partition chromotography |
| Ion exchange chromatography |
| Affinity chromatography |
| High performance liquid chromatography |
| HPTLC |
| Unit III |
| CENTRIFUGATION METHODS |
| Basic principles of sedimentation |
| centrifugal force |
| Svedberg constant |
| types of centrifuges & rotors. |
| Preparative ultracentrifugation |
| differential and density gradient. |
| Analytical ultracentrifuge |
| Unit IV |
| ELECTROPHORETIC TECHNIQUES |
| factors affecting the migration rate-electric field |
| iselius moving boundary electrophoresis |
| electrophoresis with paper |
| electophoresis with cellulose acetate |
| electophoresis with starch |
| electophoresis with agarose |
| electophoresis with polyacrylamide gel |
| SDS-PAGE |
| 2D electrophoresis |
| Immunoelectophoresis |
| High voltage electrophoresis |
| Isoelectric focusing. |
| Unit V |
| RADIOISOTOPE TECHNIQUES |
| Atomic structure, radiations, types of radioactive decay, |
| Types of radioactive decay |
| half life period |
| units of radioactivity detection |
| measurement of radioactivity |
| (GM counter & scintillation counter) |
| Autoradiography |
| elucidation of metabolic pathway |
| clinical diagnosis |
| radio dating |
| Safety aspects of the use of radio isotopes |
II B.Sc., SEMESTER– III ALLIED 4(OPTIONAL): MICROBIOLOGY – GENERAL |
| Unit I |
| HISTORY AND SCOPE OF MICROBIOLOGY |
| HISTORY AND SCOPE OF MICROBIOLOGY |
| Classification of Microorganism- Haeckel’s and Whittaker’s |
| Prokaryotes and Eukaryotes |
| Carl Woese-3 domain Concept |
| An introduction to microscopy compound |
| dark field |
| Bright field |
| Phase contrast |
| Fluorescent |
| Electron microscope. |
| Unit II |
| BACTERIA - MORPHOLOGY AND ITS GROWTH CHARACTERISTICS: |
| Bacteria Nomenclature, morphology and fine structure |
| Growth curve |
| Types of Culture medium |
| Culture methods,Cultural characteristics |
| Identification |
| Reproduction and Photosynthesis. |
| Reproduction and Photosynthesis. |
| Unit III |
| Mycoplasma |
| Rickettsiae |
| Chlamydia |
| Myxobacteria. |
| Viruses General properties |
| Types |
| TMV |
| T-even phage-Morphology |
| Reproduction. |
| Unit IV |
| Reproduction of Algae |
| Reproduction of Fungi |
| Reproduction of Protozoa |
| structure of Algae |
| Structure of Fungi |
| Structure of Protozoa |
| Micro algae :Chlorella, Volvox, Diatoms |
| Micro algae :Chlorella, Volvox, Diatoms |
| Micro algae :Chlorella, Volvox, Diatoms |
| Micro Fungi: Yeast, Mucor, Penicillium, Aspergillus |
| Micro Fungi: Yeast, Mucor, Penicillium, Aspergillus |
| Micro Fungi: Yeast, Mucor, Penicillium, Aspergillus |
| Protozoa:Entamoeba, Paramecium, Plasmodium, Trypanosoma. |
| Unit V |
| CONTROL OF MICROORGANISMS: |
| Physical Agents & Chemical Agents |
| AntibioticsClassification based on their mode of action |
| Penicillin |
| Polymyxin |
| Streptomycin |
| Sulfonamides |
| chemotherapeutic agents |
| antibiotic resistance. |
| III B.Sc.SEMESTER VI SKILL BASED ELECTIVE: - 6 RESEARCH METHODOLOGY |
| III B.Sc.SEMESTER VI NME 2: NON MAJOR ELECTIVE PAPER - II HOME MANAGEMENT |
| III B.Sc.SEMESTER -VI MAJOR ELECTIVE -3 BASICS OF BIOINFORMATICS |
| III B.Sc.SEMESTER V- NME 1: NON MAJOR ELECTIVE PAPER I FIRST AID MANAGEMENT |
| III B.Sc. SEMESTER VI MAJOR CORE 12 - CLINICAL BIOCHEMISTRY |
| III B.Sc. SEMESTER VI MAJOR CORE 11: GENETIC ENGINEERING AND BIOTECHNOLOGY |
| III B.Sc. SEMESTER V MAJOR CORE 10: CELL AND MOLECULAR BIOLOGY |
| III B.Sc. SEMESTER V MAJOR CORE 9: INTERMEDIARY METABOLISM (METABOLIC DISORDERS NOT INCLUDED) |
| III B.Sc. SEMESTER V MAJOR CORE ELECTIVE-2: BIOSTATISTICS |
| III B.Sc. SEMESTER-V MAIN CORE-7:
IMMUNOLOGY |